In practice, cholangitis, the term used to describe a clinical syndrome which, in its typical form of acute gallstone cholangitis, the associated right upper quadrant pain, fever and jaundice. It reflects an infection of the bile and an acute inflammatory disease of the walls of the bile ducts.
But the definition of cholangitis varies between schools:
In fact, says the French school, the definition of the bacterial disease andDescription cholangitis excluded as acute bacterial infection of the biliary tract Intra-and extra liver, gallbladder. And they opt for the concept of cholangitis without obstruction.
But the Anglo-Saxon define it as an infection of the bile necessarily associated an obstacle to biliary stone disease in 90% of cases. The mortality rate of cholangitis is high, especially if left untreated, and in humans, the genetic defects are associated literature reports a mortality rate ofabout 7 to 40%.
The prognosis of cholangitis is dependent on several factors:
Epidemiological factors: age, sex, associated errors, obesity ….
The type of cholangitis: In uncomplicated cholangitis, first, the mortality rate is significantly lower.
In the case of complicated cholangitis, the mortality rate is very high.
The severity of the prognosis of cholangitis is composed of several causes, they are either occurring in theimmediate postoperative acute pancreatitis, bile peritonitis, gastrointestinal bleeding or recurrence of septic symptoms, renal failure, but they can also be the result of the operational procedures of wrongdoing or local adverse operating conditions, or the cause of cholangitis, as in the case of neoplasia.
The following factors are associated with high morbidity and mortality:
Women. Age> 50 years. Hypotension. Renal failure. The liver abscess.Liver cirrhosis. The radiological cholangitis (post-percutaneous cholangiography). Lack of response to antibiotic therapy and medical treatment. Longer time decompression of the biliary tract.
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